2011 Fiscal Year Final Research Report
Intracellular manipulation of proteins in neurons with resonance laser beam
| Project/Area Number |
21710123
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
HOSOKAWA Chie 独立行政法人産業技術総合研究所, 健康工学研究部門, 研究員 (60435766)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 光ピンセット / ナノバイオ / 脳 / 神経 / 生物物理 |
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| Research Abstract |
Biological systems form complex networks related with functional molecules and are dynamically affected by spatio-temporal regulations. For aiming artificial control of the systems, we proposed and demonstrated intracellular manipulation of neural cell adhesion molecules(NCAMs) on living neuronal cells using resonance and nonresonance laser beams. The intracellular motion of NCAMs labeled with quantum dots was evaluated by fluorescence correlation spectroscopy.
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