2010 Fiscal Year Final Research Report
Synthetic and biological studies of chondroitin sulfate and dermatan sulfate partial structure which potentially associate with neurite growth-promoting activity.
| Project/Area Number |
21710233
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Living organism molecular science
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| Research Institution | Kagoshima University |
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Principal Investigator |
WAKAO Masahiro Kagoshima University, 理工学研究科(工学系), 助教 (20404535)
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| Project Period (FY) |
2009 – 2010
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| Keywords | コンドロイチン硫酸 / デルマタン硫酸 / 糖鎖合成 / 神経突起伸長活性 |
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| Research Abstract |
Chondrotin sulfate (CS) and dermatan sulfate (DS), which are belonging to sulfated glycosaminoglycan, have been reported to exhibit neurite outgrowth activity against nerve cells. In this study, to investigate structure and activity relationships of CS and DS at the molecular level, we examined the synthesis of CS and DS partial structures.
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