Chemical biology on Phytophthora mating hormone α1

2010 Fiscal Year Final Research Report

• Project/Area Number: 21710239
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Living organism molecular science
• Research Institution: Tokyo University of Agriculture
• Principal Investigator: YAJIMA Arata Tokyo University of Agriculture, 応用生物科学部, 准教授 (30328546)
• Project Period (FY): 2009 – 2010
• Keywords: ケミカルバイオロジー / 疫病菌 / Phytophthora / 化学プローブ / 有機合成化学 / 全合成

Research Abstract

The novel sexual oospore inducing hormone α2 produced by A2 mating type of Phytophthora was synthesized. The absolute configuration of the natural product was determined. The chemical probes of hormone α1 derivatives were also prepared.

Research Products

• [Presentation] Shylaja, Harumi Kanazawa, Tomoo Nukada, Youji Sakagami, Goro Yabuta (2009)
  • Author(s): Arata Yajima, Makoto Ojika, Keisuke Shikai, Tadashi Imaoka, Tomoyo Asano, Jinhua Qi, Molli D.
  • Organizer: Synthesis and SAR studies of Phytophthora mating hormone a1(IKCOC-11)
  • Place of Presentation: 京都
  • Year and Date: 20091100
• [Presentation] Synthetic studies on agriculturally important bioactive natural compounds (2009)
  • Author(s): Arata Yajima
  • Organizer: 5th Sino-Japanese Symposium on Organic Chemistry for Young Scientists
  • Place of Presentation: Chengdu
  • Year and Date: 20091000
• [Presentation] 疫病菌Phytophthoraの繁殖誘導ホルモンa1の構造活性相関 (2009)
  • Author(s): 四海圭祐、今岡忠、浅野友世、威建華、Mollid Shylaja、金沢晴海、小鹿一、矢島新、額田恭郎、薮田五郎
  • Organizer: 日本農芸化学会年度大会
  • Place of Presentation: 福岡
  • Year and Date: 20090300