2011 Fiscal Year Final Research Report
Elucidation of functions of proteins in terms of dynamical interactions between proteins and water molecules
| Project/Area Number |
21740307
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | タンパク質 / 水 / エネルギー論 / Lagrange協同構造 / Koopman演算子 |
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| Research Abstract |
Functions of proteins can be understood in terms of the way of how the proteins response to external stimuli and consecutive chemical reactions and conformational changes triggered by the stimuli. For these chemical reactions and conformational changes, the surrounding water molecules play an important role. Here, molecular mechanisms of how the surrounding water molecules assist or hinder the conformational changes of a peptide, which has the similar properties as proteins, is elucidated in terms of energetics, Lagrangian Coherent Structure, Koopman operator.
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Research Products
(10 results)
