2010 Fiscal Year Final Research Report
Exploitation of the unique reactivity of diazocarbonyl compounds for the development of practical synthetic methods
Project/Area Number |
21750041
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Organic chemistry
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Research Institution | Kyoto University |
Principal Investigator |
HASHIMOTO Takuya Kyoto University, 大学院・理学研究科, 助教 (20437198)
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Project Period (FY) |
2009 – 2010
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Keywords | ジアゾ化合物 / 酸触媒 / 触媒的不斉合成 |
Research Abstract |
This research project was aimed at the development of novel synthetic methods based on the use of α-diazocarbonyl compounds, as it was anticipated to reveal straightforward ways for the preparation of complex molecules. This study led to the finding of novel synthetic methods for valuable synthetic building blocks, such as seven-membered carbocycles, β-keto carbonyl compounds and aziridines, which are commonly seen in anticancer drugs and other biologically active materials.
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