2011 Fiscal Year Final Research Report
Development and Application of Practical Methodology to Access Biologically Active Alkaloids Using Alkoxyamide
| Project/Area Number |
21750049
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Keio University |
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Principal Investigator |
SATO Takaaki 慶應義塾大学, 理工学部, 助教 (70509926)
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| Project Period (FY) |
2009 – 2011
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| Keywords | アミド / アルコキシアミド / 求核付加反応 / タンデム反応 / ゲフィロトキシン |
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| Research Abstract |
Amide functional groups play a significant role in a variety of areas such as medicinal drugs and chemical fibers. Therefore, organic chemists have developed the efficient synthesis of amide bonds. On the other hand, functionalization of the generated amide carbonyl groups is less explored than their construction due to the high stability of the amide. In this study, we succeeded to functionalize the amide group using the unique properties of alkoxyamides.
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