2011 Fiscal Year Final Research Report
Development of fluorescent reagents for the real-time imaging of intracellular redox state
| Project/Area Number |
21750077
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
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| Research Institution | Saga University (2011)
Kyushu University (2009-2010) |
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Principal Investigator |
SOH Nobuaki 佐賀大学, 農学部, 准教授 (90336008)
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| Research Collaborator |
IMATO Toshihiko 九州大学, 大学院・工学研究院, 教授 (50117066)
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| Project Period (FY) |
2009 – 2011
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| Keywords | レドックス / 蛍光 |
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| Research Abstract |
Novel fluorescent reagents were developed for monitoring redox state. The fluorescent reagents(Cy-NQ, PBI-AQ) consist of fluorophore unit(cyanine(Cy), perylene bisimide(PBI)) and redox-responsive unit(naphthoquinone(NQ), anthraquinone(AQ). Fluorescent responses of the fluorescent reagents were observed based on the redox reactions.
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