2010 Fiscal Year Final Research Report
The development of catalytic cross-couplings using anisole derivatives
| Project/Area Number |
21750100
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
TOBISU Mamoru 大阪大学, 工学研究科, 特任講師(常勤) (60403143)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 均一系触媒 / 遷移金属錯体 / 不活性結合切断 |
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| Research Abstract |
Inert phenol derivatives, such as anisole, can be employed as an aryl halide surrogate. The key to success is the combined use of a nickel catalyst and bulky and electron-rich ligands. The Suzuki-Miyaura type reaction using organoboron reagents, amination using secondary amines, and reductive cleavage using hydrosilane have been developed.
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