2010 Fiscal Year Final Research Report
Development of Photoresponsive Bioactive Molecules
| Project/Area Number |
21750163
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemistry related to living body
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2010
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| Keywords | 生体認識 / 機能化学 |
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| Research Abstract |
Spatial control of cell activities has been studied with photo-responsive hydro-gels in which photo-irradiated area turns into bio-active. Peptidic amphiphiles (PAs) including Arg-Gly-Asp sequence, an epitope to induce cell adhesion, with aphotocleavable protecting group has been used. In the case that glycine was protected, a PA performing solution to gel photo conversion, palmitoyl-V2E2RGDS, was obtained, where light-triggered cell adhesion with fixing cells in three-dimensional media by the photo-gelation.
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Research Products
(29 results)
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[Presentation] 高次構造を有する両親媒性マルチブロックオリゴマーの開発2011
Author(s)
Takahiro Muraoka, Tatsuya Shima, Tsutomu Hamada, Masamune Morita, Masahiro Takagi, Kazushi Kinbara
Organizer
平成22年度附置研究所間アライアンスによるナノとマクロをつなぐ物質・デバイス・システム創製戦略プロジェクト成果報告会
Place of Presentation
仙台
Year and Date
2011-03-07
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