2013 Fiscal Year Final Research Report
Studies on synthesis and evaluation of regioselectively substituted polysaccharide derivatives
| Project/Area Number |
21750224
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Polymer/Textile materials
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| Research Institution | Suzuka National College of Technology |
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Principal Investigator |
YAMAMOTO Chiyo 鈴鹿工業高等専門学校, 生物応用化学科, 准教授 (80314045)
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| Project Period (FY) |
2009-04-01 – 2014-03-31
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| Keywords | 多糖 / 光学分割 / セルロース / アミロース / ＨＰＬＣ / 位置特異的 |
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| Research Abstract |
Polysaccharides such as cellulose and amylose are some of the most readily available optically active polymers. Although these polymers have stereoregular sequences consisting of D-glucose, their chiral recognition abilities are not large. However, these polysaccharides have hydroxyl groups which can be readily converted to esters and carbamates. In this study, the novel regioselectively substituted cellulose and amylose have been synthesized, and their abilities of enantiomer resolution in high-performance liquid chromatography (HPLC) have been evaluated. These derivatives exhibited the relatively high chiral recognition abilities comparable or better to the derivatives with the same substituent at all hydroxyl groups.
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