2011 Fiscal Year Final Research Report
Numerical Simulation of Biological Cell Behavior in Fluid Channel by Using Interface Capturing Method
| Project/Area Number |
21760136
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fluid engineering
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| Research Institution | Keio University |
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Principal Investigator |
FUKAGATA Koji 慶應義塾大学, 理工学部, 准教授 (80361517)
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| Project Period (FY) |
2009 – 2011
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| Keywords | バイオ流体力学 |
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| Research Abstract |
In this study, we aimed at developing a numerical simulation method that can handle fluid flows containing biological cells by extending the interface capturing methods used for numerical simulation of two-phase flows, which have light computational load. We developed a new method based on the combination of the Level Set Method and an isotropic elastic membrane model. In particular, we proposed a formulation utilizing the level set function to represent the displacement of the membrane in the Eulerian frame and its effectiveness was confirmed. In addition, to handle the collision of multiple cells, we proposed a repulsive force model utilizing the level set function and its effectiveness was also confirmed.
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