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2010 Fiscal Year Final Research Report

Breast Cancer Diagnosis by Optical Imaging with Inverse Problem of Source Estimation

Research Project

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Project/Area Number 21760312
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Measurement engineering
Research InstitutionThe University of Electro-Communications

Principal Investigator

OKAWA Shinpei  The University of Electro-Communications, 大学院・情報理工学研究科, 助教 (20432049)

Co-Investigator(Renkei-kenkyūsha) YAMADA Yukio  電気通信大学, 大学院・情報理工学研究科, 教授 (10334583)
Project Period (FY) 2009 – 2010
Keywords信号処理 / 逆問題
Research Abstract

The algorithms to solve the inverse problems in the optical imaging using near-infrared light for diagnoses of breast cancer were studied. The technique for reconstructing fluorescent light sources in biological media by use of spatial filter was proposed. The method to reduce noise in the time-resolved measurement data using maximum a priori estimation was also developed. The proposed methods were validated with the numerical simulations and the phantom experiments. Efficient arrangement of the light sources and detectors for diffuse optical tomography was also investigated.

  • Research Products

    (7 results)

All 2011 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results)

  • [Journal Article] Reduction of Poisson noise in measured time-resolved data for time-domain diffuse optical tomography2011

    • Author(s)
      S.Okawa, Y.Endo, Y.Hoshi, Y.Yamada
    • Journal Title

      Medical and Biological Engineering and Computing DOI: 10.1007/s11517-011-0774-7

    • Peer Reviewed
  • [Journal Article] Reconstruction of fluorescence/bioluminescence sources in biological medium with spatial filter2010

    • Author(s)
      S.Okawa, Y.Yamada
    • Journal Title

      Optics Express 13(12)

      Pages: 13151-13172

    • Peer Reviewed
  • [Presentation] Effect of the Arragngement of Optodes for 3D Diffuse Optical Tomography2011

    • Author(s)
      K.Uchida, S.Okawa, K.Masamoto, Y.Hoshi, Y.Yamada
    • Organizer
      Proc.of the ASME/JSME 2011 8th Thermal Engineering Joint Conference AJTEC2011-44480
    • Place of Presentation
      Honolulu, Hawaii, USA.
    • Year and Date
      20110313-20110317
  • [Presentation] Source Reconstruction with Spatial Filter and Reduction of Artifacts in Fluorescence/Bioluminescence Diffuse Optical Tomography2010

    • Author(s)
      S.Okawa, Y.Yamada
    • Organizer
      Proc.of SICE Annual Conference 2010 3223-3224
    • Place of Presentation
      Taipei, Taiwan.
    • Year and Date
      20100818-20100822
  • [Presentation] Reduction of Poisson Noise for Time-Resolved Diffuse Optical Measurement2010

    • Author(s)
      S.Okawa, Y.Yamada
    • Organizer
      Proc.of SICE Annual Conference 2010 91-592
    • Place of Presentation
      Taipei, Taiwan.
    • Year and Date
      20100818-20100821
  • [Presentation] 3次元拡散光トモグラフィのシミュレーション2010

    • Author(s)
      内田和浩, 松橋翔子, 星詳子, 大川晋平, 山田幸生
    • Organizer
      第23回バイオエンジニアリング講演会講演論文集 366
    • Place of Presentation
      岡山
    • Year and Date
      20100108-20100809
  • [Presentation] 3D light source reconstruction with spatial filter for fluorescence/bioluminescence diffuse optical tomography2009

    • Author(s)
      S.Okawa, Y.Yamada
    • Organizer
      Proc.of SPIE Vol.7369, Progress in Biomedical Optics and Imaging 10(45) 736916
    • Place of Presentation
      Munich, Germany.
    • Year and Date
      20090614-20090617

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Published: 2012-02-13   Modified: 2016-04-21  

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