Enhancement of water durability and bio-activity on electrically modified yttria-stabilized zirconia surfaces

2010 Fiscal Year Final Research Report

• Project/Area Number: 21760528
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Inorganic materials/Physical properties
• Research Institution: Kyushu University
• Principal Investigator: TANAKA Yumi Kyushu University, 大学院・工学研究院, 准教授 (00436619)
• Project Period (FY): 2009 – 2010
• Keywords: イットリア安定化正方晶ジルコニア / バイオセラミックス / 酸化物イオン伝導 / 分極 / 低温劣化 / アルカリ処理 / 骨類似アパタイト

Research Abstract

Yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) is an important load-bearing bioceramic. However, a phenomenon called LTD, in which a phase destabilization occurs under moisture, reduces the reliability of Y-TZP as long-term implants. Since the exact mechanism of LTD is still unclear, this work was directed to evaluate an influence of surface charges of Y-TZP on LTD. Y-TZP were polarized under DC electrical field to vary surface O^<2-> concentrations, which resulted in a successful preparation of Y-TZP surfaces with stable static charges. LTD durability was significantly influenced by the polarity on the surfaces ; the negatively-charged surface was proved to show a good LTD durability.

Research Products

• [Journal Article] Fast oxide ion conduction due to carbonate substitution in hydroxyapatite (2010)
  • Author(s): Y.Tanaka, M.Kikuchi, K.Tanaka, K.Hashimoto, J.Hojo, M.Nakamura, A.Nagai, T.Sugiyama, F.Munakata, K.Yamashita
  • Journal Title: J.Am.Ceram.Soc. 93[11] Pages: 3577-3579
  • Peer Reviewed
• [Journal Article] Effect of Ionic Polarization on Crystal Structure of Hydroxyapatite Ceramic with Hydroxide Nonstoichiometry (2010)
  • Author(s): Y.Tanaka, T.Iwasaki, K.Katayama, J.Hojo, K.Yamashita
  • Journal Title: J.Jpn.Soc.Powder Powder Metallurgy 57[7] Pages: 520-528
  • Peer Reviewed
• [Journal Article] Biocompatibility and LTD durability of alumina-zirconia ceramics blended with microsized HA particles (2010)
  • Author(s): Y.Tanaka, M.Yoshida, M.Nakamura, A.Nagai, K.Hashimoto, Y.Toda, K.Yamashita
  • Journal Title: J.Ceram.Soc.Jpn 118[6] Pages: 498-501
  • Peer Reviewed
• [Journal Article] Synthesis of Ca_3Sc_2Si_3O_<12>:Ce^<3+> phosphor via newly developed emulsion route (2010)
  • Author(s): N.Enomoto, T.Sakai, M.Inada, Y.Tanaka, J.Hojo
  • Journal Title: J.Ceram.Soc.Jpn. 118[1383] Pages: 1067-1070
  • Peer Reviewed
• [Journal Article] Polarization of hybridized calcium phosphoaluminosilicates with 45S5-type bioglasses (2010)
  • Author(s): M.Kobayashi, H.Saito, T.Mase, T.Sasaki, W.Wang, Y.Tanaka, M.Nakamura, A.Nagai, K.Yamashita
  • Journal Title: Biomed.Mater. 5[2-025001] Pages: 1-5
  • Peer Reviewed
• [Journal Article] Polarization and microstructural consideration of ceramic hydroxyapatite electrets (2010)
  • Author(s): Y.Tanaka, T.Iwasaki M.Nakamura, A.Nagai, K.Katayama, K.Yamashita
  • Journal Title: Journal of Applied Physics 107 Pages: 014107-1-014107-10
  • Peer Reviewed
• [Journal Article] Biocompatibility and water durability of alumina-zirconia ceramics blended with a small amount of HA nanoparticles (2009)
  • Author(s): Y.Tanaka, M.Yoshida, M.Nakamura, A.Nagai, K.Hashimoto, Y.Toda, K.Yamashita
  • Journal Title: Archives of BioCeramics Research 9 Pages: 79-82
  • Peer Reviewed
• [Journal Article] Transformation of OCP-based cement filled in root canal to hydroxyapatite (2009)
  • Author(s): Y.Imamura, Y.Tanaka, K.Yamashita, Y.Takagi
  • Journal Title: Dental Materials 25[5] Pages: 13-14
• [Journal Article] Controlled Crystallization of Calcite Under Surface Electric Field Due to Polarized Hydroxyapatite Ceramics (2009)
  • Author(s): N.Wada, Y.Tanaka, M.Nakamura, K.Kanamura, K.Yamashita
  • Journal Title: Journal of the American Ceramic Society 92[7] Pages: 1586-1591
  • Peer Reviewed
• [Journal Article] Comparison of enhancement of bone ingrowth into hydroxyapatite ceramics with highly and poorly interconnected pores by electrical polarization (2009)
  • Author(s): W.Wang, S.Itoh, Y.Tanaka, A.Nagggai, K.Yamashita
  • Journal Title: Acta Biomaterialia 5[8] Pages: 3132-3140
  • Peer Reviewed
• [Journal Article] Polarized hydroxyapatite promotes spread and motility of osteoblastic cells (2009)
  • Author(s): M.Nakamura, A.Nagai, Y.Tanaka, Y.Sekijima, K.Yamashita
  • Journal Title: Journal of Biomedical Materials Research Part A 92A Pages: 783-790
  • Peer Reviewed
• [Journal Article] Efficacy of polarized hydroxyapatite and silk fibroin composite dressing on epidermal recovery from full-thickness porcine skin wounds (2009)
  • Author(s): R.Okabayashi, M.Nakamura, T.Okabayashi, Y.Tanaka, A.Nagai, K.Yamashita
  • Journal Title: Journal of Biomedical Materials Research Part B-Applied Biomaterials 90B[2] Pages: 641-646
  • Peer Reviewed
• [Journal Article] Ion conduction mechanism in Ca deficient hydroxyapatite whisker (2009)
  • Author(s): Y.Tanaka, M.Nakamura, A.Nagai, T.Toyama, K.Yamashita
  • Journal Title: Materials Science and Engineering : B 160 Pages: 115-119
  • Peer Reviewed
• [Journal Article] Formation of Calcite Thin Films by Cooperation of Polyacrylic Acid and Self-generating Electric Field due to Aligned Dipoles of Polarized Substrates (2009)
  • Author(s): N.Wada, M.Nakamura, Y.Tanaka, K.Kanamura, K.Yamashita
  • Journal Title: Journal of Colloid and Interface Science 330 Pages: 374-379
  • Peer Reviewed
• [Presentation] ジルコニアセラミックスの低温劣化に対する表面電荷の影響 (2011)
  • Author(s): 原浩之、田中優実、稲田幹、榎本尚也、永井亜希子、山下仁大、北條純一
  • Organizer: 日本セラミックス協会2011年年会
  • Place of Presentation: 静岡(静大)
  • Year and Date: 2011-03-18
• [Presentation] マイクロ波水熱炭化法によるカーボンスフィアの合成 (2011)
  • Author(s): 古賀貴寛、稲田幹、田中優実、榎本尚也、北條純一
  • Organizer: 日本セラミックス協会2011年年会
  • Place of Presentation: 静岡(静大)
  • Year and Date: 2011-03-18
• [Presentation] ナノ粒子の溶液合成におけるアンコンシャスプロセス因子 (2011)
  • Author(s): 榎本尚也、木村純平、稲田幹、田中優実、北條純一
  • Organizer: 日本セラミックス協会2011年年会
  • Place of Presentation: 静岡(静大)
  • Year and Date: 2011-03-16
• [Presentation] 固体アイオニクス技術を活用した新型エレクトレットの開発 (2011)
  • Author(s): 田中優実
  • Organizer: 三次元ナノ・マイクロ構造研究集会
  • Place of Presentation: 大阪(阪大)
  • Year and Date: 2011-03-11
• [Presentation] Effects of Electrical Modification on Phase Stability of Y-TZP Ceramics (2011)
  • Author(s): Y.Tanaka, H.Hara, N.Enomoto, K.Yamashita, J.Hojo
  • Organizer: 35^th International Conference on Advanced Ceramics and Composites
  • Place of Presentation: Florida, USA
  • Year and Date: 2011-01-25
• [Presentation] 炭素還元窒化法によるSiC-AlN固溶体の作製及びSPS焼結 (2011)
  • Author(s): 張琳琳、田中優実、榎本尚也、北條純一
  • Organizer: 第49回セラミックス基礎科学討論会
  • Place of Presentation: 岡山
  • Year and Date: 2011-01-11
• [Presentation] 酸化物イオン伝導を利用したジルコニアセラミックエレクトレットの創生 (2011)
  • Author(s): 田中優実、原浩之、稲田幹、榎本尚也、山下仁大、北條純一
  • Organizer: 第49回セラミックス基礎科学討論会
  • Place of Presentation: 岡山
  • Year and Date: 2011-01-11
• [Presentation] イットリア安定化ジルコニアの相転移に及ぼす表面電荷の影響 (2010)
  • Author(s): 原浩之、田中優実、山下仁大、北條純一
  • Organizer: 第14回生体関連セラミックス討論会
  • Place of Presentation: 京都
  • Year and Date: 2010-12-03
• [Presentation] プロトン伝導の利用によるハイドロキシアパタイトエレクトレットの創生 (2010)
  • Author(s): 田中優実、北條純一、山下仁大
  • Organizer: 第36回固体イオニクス討論会
  • Place of Presentation: 仙台
  • Year and Date: 2010-11-25
• [Presentation] Effective Storage of Electrical Charge in Hydroxyapatite Ceramics Using Ionic Conductive Property (2010)
  • Author(s): Y.Tanaka, M.Nakamura, H.Junichi, A.Nagai, K.Yamashita
  • Organizer: 3^rd International Congress on Ceramics
  • Place of Presentation: Osaka (Japan)
  • Year and Date: 2010-11-17
• [Presentation] Innovative design for new bioceramics (2010)
  • Author(s): Y.Tanaka
  • Organizer: Seminar on International Engineering Education-Lund University and Kyushu University
  • Place of Presentation: Fukuoka (Japan)
  • Year and Date: 2010-11-15
• [Presentation] 水酸アパタ イトセラミックスの電場下における静電エネルギー蓄積メカニズム (2010)
  • Author(s): 田中優実、北條純一、山下仁大
  • Organizer: 2010年セラミックス総合研究会
  • Place of Presentation: 北海道(北大)
  • Year and Date: 2010-09-02
• [Presentation] エレクトレットの新展開～様々なエネルギー変換の形～ (2010)
  • Author(s): 田中優実
  • Organizer: 第3回循環センター研究交流会
  • Place of Presentation: 福岡(九大)
  • Year and Date: 2010-07-05
• [Presentation] ハイドロキシアパタイトセラミックスへの非化学量論性導入と分極効果 (2010)
  • Author(s): 田中優実、北條純一、山下仁大
  • Organizer: 粉体粉末冶金協会22年度春季大会
  • Place of Presentation: 東京(早大)
  • Year and Date: 2010-05-25
• [Presentation] 生体に刺激を与える生体親和性セラミックスの創生にむけて (2010)
  • Author(s): 田中優実
  • Organizer: 日本材料学会平成21年度第2回ナノ材料部門委員会講演会
  • Place of Presentation: 京都
  • Year and Date: 2010-02-17
• [Presentation] B型炭酸含有アパタイトの酸化物イオン伝導機構 (2010)
  • Author(s): 田中優実、田中一正、萩原梓、橋本和明、戸田善朝、杉山龍男、宗像文男、山下仁大
  • Organizer: 第48回セラミックス基礎討論会
  • Place of Presentation: 沖縄
  • Year and Date: 2010-01-12
• [Presentation] Preparation and characterization of ceramic hydroxyapatite electrets for biomedical utilization (2010)
  • Author(s): Y.Tanaka, T.Iwasaki, M.Nakamura, A.Nagai, K.Katayama, K.Yamashita
  • Organizer: The 11^th international symposium on eco-materials processing and design (ISEPD2010)
  • Place of Presentation: Osaka (Japan)
  • Year and Date: 2010-01-10
• [Presentation] Biocompatibility and water durability of alumina-zirconia ceramics blended with a small amount of HA nanoparticles (2009)
  • Author(s): Y.Tanaka, M.Yoshida, M.Nakamura, A.Nagai, K.Hashimoto, Y.Toda, K.Yamashita
  • Organizer: 9^th Asian Bioceramics symposium
  • Place of Presentation: Nagoya (Japan)
  • Year and Date: 2009-12-09
• [Presentation] In Vitro Method to Characterize Resorption of Calcium Phosphate-Based Ceramic Scaffolds (2009)
  • Author(s): A.Ito, Y.Sogo, A.Yamazaki, M.Aizawa, A.Osaka, S.Hayakawa, M.Kikuchi, I.Akahane, K.Yamashita, Y.Tanaka, M.Tadokoro, H.Ohgushi
  • Organizer: The 26^th International Japan-Korea Seminar on Ceramics
  • Place of Presentation: Ibaraki (Japan)
  • Year and Date: 2009-11-25
• [Presentation] Consideration of electrochemical property of biocompatible B-type carbonated apatite (2009)
  • Author(s): Y.Tanaka, A.Hagiwara, A.Nagai, T.Sugiyama, F.Munakata, K.Hashimoto, K.Yamashita
  • Organizer: The 26^th International Japan-Korea Seminar on Ceramics
  • Place of Presentation: Ibaraki (Japan)
  • Year and Date: 2009-11-25
• [Presentation] 電場活性空間を有する生体用ハイドロキシアパタイトの創製 (2009)
  • Author(s): 田中優実、中村美穂、永井亜希子、山下仁大
  • Organizer: 粉体粉末冶金協会平成21年度秋季大会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-10-28
• [Presentation] 分極アパタイトによる骨芽細胞挙動制御 (2009)
  • Author(s): 中村美穂、永井亜希子、田中優実、山下仁大
  • Organizer: 第54回日本歯科理工学会学術講演会
  • Place of Presentation: 鹿児島
  • Year and Date: 2009-10-02
• [Presentation] アルミナ混合Y-TZPセラミックスの低温劣化抑制に及ぼすHA微量添加効果 (2009)
  • Author(s): 田中優実、中村美穂、永井亜希子、山下仁大
  • Organizer: 第54回日本歯科理工学会学術講演会
  • Place of Presentation: 鹿児島
  • Year and Date: 2009-10-02
• [Presentation] ハイドロキシアパタイトエレクトレットの分極緩和機構 (2009)
  • Author(s): 田中優実、岩崎健、片山恵一、永井亜希子、山下仁大
  • Organizer: セラミックス協会第22回秋季シンポジウム
  • Place of Presentation: 愛媛
  • Year and Date: 2009-09-18
• [Presentation] Ionic conduction mechanism of B-type carbonated apatite (2009)
  • Author(s): Y.Tanaka, M.Sasaki, A.Nagai, T.Sugiyama, F.Munakata, M.Nagai, T.Okura, K.Yamashita
  • Organizer: 17^th Conference on Solid State Ionics
  • Place of Presentation: Toronto, Canada
  • Year and Date: 2009-07-03
• [Presentation] 分極水酸アパタイト局所場による表面機能制御 (2009)
  • Author(s): 中村美穂、大倉利典、田中優実、永井亜希 子、山下仁大
  • Organizer: 無機マテリアル学会第118回学術講演会
  • Place of Presentation: 千葉
  • Year and Date: 2009-06-04
• [Presentation] 炭酸含有アパタイトの分極特性に及ぼす炭酸イオンの効果 (2009)
  • Author(s): 田中優実、笹木眞澄、宗像文男、中村美穂、永井亜希子、大倉利典、門間英毅、山下仁大
  • Organizer: 無機マテリアル学会第118回学術講演会
  • Place of Presentation: 千葉
  • Year and Date: 2009-06-04
• [Presentation] Evaluating the Durability of Phosphoric Acid Promoted Bioglass-dentin Interaction Layer, IADR/AADR/CADR (2009)
  • Author(s): A.S.Bakry, K.Matin, Y.Tanaka, M.Otsuki, H.Takahashi, K.Yamashita, J.Tagami
  • Organizer: 87^th General Session & Exhibition
  • Place of Presentation: Florida, USA
  • Year and Date: 2009-04-03