2010 Fiscal Year Final Research Report
Establishment of In Vivo Non-Destructive and Less-Invasive method for Analyzing Bone Quality
Project/Area Number |
21760558
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Structural/Functional materials
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Research Institution | Osaka University |
Principal Investigator |
ISHIMOTO Takuya Osaka University, 工学研究科, 助教 (50508835)
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Project Period (FY) |
2009 – 2010
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Keywords | 骨質 / 生体アパタイト / 配向性 / 微小領域X線回折法 / 透過型光学系 / 骨力学機能 / 低侵襲化 |
Research Abstract |
For extracted bones (ex vivo), quantitative analysis of the preferred orientation of biological apatite was successfully achieved by using a microbeam X-ray diffraction technique with a transmission optical system. The analytical condition was optimized based on the X-ray absorption coefficient of bone tissue and bone morphology. To expand this technique for in vivo (non-extracted) bone, X-ray absorption profile was taken for the detection of bone totally inside of soft tissues. By combining these techniques, it was possible to detect bone and obtain X-ray diffraction information from bone in vivo. This means the in vivo non-destructive and less-invasive method for analyzing bone quality was established in this study.
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Research Products
(18 results)
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[Remarks] 阪本達志,石本卓也, 野貴由:平成22年度日本金属学会・鉄鋼協会関西支部材料開発研究会ポスターセッション研究発表優秀賞「頭蓋顔面インプラントの設計・開発のための頭蓋骨の骨微細構造解析」に対して,平成22年度日本金属学会・鉄鋼協会関西支部材料開発研究会,大阪大学吹田キャンパス,大阪,2011年12月14日.