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2010 Fiscal Year Final Research Report

Surface modification of titanium by pack cementation process for improvement of bone compatibility

Research Project

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Project/Area Number 21760574
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Material processing/treatments
Research InstitutionTohoku University

Principal Investigator

UEDA Kyosuke  東北大学, 大学院・工学研究科, 助教 (40507901)

Co-Investigator(Renkei-kenkyūsha) NARUSHIMA Takayuki  東北大学, 大学院・工学研究科, 教授 (20198394)
Project Period (FY) 2009 – 2010
Keywordsチタン / 表面処理 / リン酸カルシウム / パックセメンテーション法 / 密着力 / アパタイト / 生体外評価 / 細胞培養試験
Research Abstract

Calcium phosphate reaction layers were fabricated on titanium by pack cementation process, isobaric-isothermal process and their combination process to improve the bonecompatibility of titanium. The phase of the reaction layer was hydroxyapatite (HAp) and Ca-P-O-Ti graded layer, and its thickness was several μm. The reaction layer showed high bonding strength to the substrate and high ALP activity by the cell culture test. These results suggested that the new process effectively improved the bone compatibility of titanium.

  • Research Products

    (15 results)

All 2011 2010 2009

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (8 results) Book (1 results)

  • [Journal Article] Surface modification of titanium by pack cementation treatment using calcium phosphate powders for biomedical applications2010

    • Author(s)
      K. Ueda, H. Suto, T. Narushima
    • Journal Title

      Met. Mater. Int.

      Volume: 4 Pages: 569-572

    • Peer Reviewed
  • [Journal Article] Pack cementation treatment of titanium using tetracalcium phosphate powder for biomedical applications2010

    • Author(s)
      K. Ueda, H. Suto, K. Nakaie, T. Narushima
    • Journal Title

      Mater. Sci. Forum

      Volume: 654-656 Pages: 2172-2175

    • Peer Reviewed
  • [Journal Article] Calcium phosphate coating on titanium using dry process2010

    • Author(s)
      T. Narushima, K. Ueda, T. Goto, J. Kurihara, H. Kawamura
    • Journal Title

      Mater. Sci. Forum

      Volume: 654-656 Pages: 2162-2167

    • Peer Reviewed
  • [Journal Article] チタン上への多層リン酸カルシウム膜の作製とその評価2010

    • Author(s)
      上田恭介, 川崎雄城, 後藤孝, 栗原淳, 川村仁, 成島尚之
    • Journal Title

      粉体および粉末冶金

      Volume: 57 Pages: 314-320

    • Peer Reviewed
  • [Journal Article] Surface modification of titanium by dry process for biomedical applications2009

    • Author(s)
      T. Narushima, K. Ueda, T. Goto
    • Journal Title

      Proceedings of the 9^<th> Int. Symp. On Biomaterials

      Pages: 22-27

    • Peer Reviewed
  • [Journal Article] Calcium phosphate films with/without heat treatments fabricated using RF magnetron sputtering2009

    • Author(s)
      K. Ueda, Y. Kawasaki, T. Narushima, T. Goto, J. Kurihara, H. Nakagawa, H. Kawamura
    • Journal Title

      J. Biomech. Sci. Eng.

      Volume: 4 Pages: 392-403

    • Peer Reviewed
  • [Presentation] ドライプロセスを利用したチタンの骨適合化表面処理2011

    • Author(s)
      上田恭介
    • Organizer
      日本金属学会・日本鉄鋼協会東海支部第58回若手材料研究会「生体材料の進展」
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2011-01-25
  • [Presentation] In vitro evaluation of pack cementation treated titanium using tetracalcium phosphate powder2010

    • Author(s)
      K. Ueda, K. Nakaie, H. Suto, T. Narushima, M. Taira
    • Organizer
      International Workshop on Nano, Bio and Amorphous Materials
    • Place of Presentation
      Tohgatta, Japan
    • Year and Date
      20100809-10
  • [Presentation] Pack cementation treatment of titanium using tetracalcium phosphate powder for biomedical applications2010

    • Author(s)
      K. Ueda, H. Suto, K. Nakaie, T. Narushima
    • Organizer
      The 7^<th> Pacific Rim International Conference on Advanced Materials and Processing
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      20100802-06
  • [Presentation] リン酸四カルシウム粉末を用いたパックセメンテーション法によるチタンの表面改質2010

    • Author(s)
      上田恭介, 須藤初, 中家香織, 成島尚之
    • Organizer
      日本金属学会第146回大会
    • Place of Presentation
      筑波大学
    • Year and Date
      20100328-30
  • [Presentation] リン酸四カルシウムを用いたパックセメンテーション法により表面処理したチタンの生体外評価2010

    • Author(s)
      上田恭介, 中家香織, 平雅之, 成島尚之
    • Organizer
      軽金属学会第118回春季大会
    • Place of Presentation
      関西大学
    • Year and Date
      2010-05-22
  • [Presentation] Bioceramics coating on titanium materials2010

    • Author(s)
      K. Ueda
    • Organizer
      International Cooperation between KITECH and Tohoku University, Korea Institute of Industrial Technology (KITECH)
    • Place of Presentation
      Songdo, Korea
    • Year and Date
      2010-02-25
  • [Presentation] リン酸四カルシウム粉末を用いたパックセメンテーション法によるチタンの骨適合化表面改質2009

    • Author(s)
      上田恭介, 須藤初, 中家香織, 成島尚之
    • Organizer
      粉体粉末冶金協会平成21年度秋季大会研究発表
    • Place of Presentation
      名古屋
    • Year and Date
      20091027-29
  • [Presentation] パックセメンテーション法によるチタンの骨適合化表面改質2009

    • Author(s)
      上田恭介, 須藤初, 成島尚之
    • Organizer
      東北大学金属材料研究所共同研究ワークショップ
    • Place of Presentation
      東北大学
    • Year and Date
      20090728-29
  • [Book] Bio-ceramic coating on titanium by physical and chemical vapor deposition2011

    • Author(s)
      T. Goto, T. Narushima, K. Ueda
    • Publisher
      In CRC Handbook of Biological and Biomedical Coatings, Ed. By S. Zhang, CRC Press, Boca Raton, FL (in press)

URL: 

Published: 2013-07-31  

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