2010 Fiscal Year Final Research Report
Regulation of post-translational modifications through fat-soluble ligands
| Project/Area Number |
21770134
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional biochemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
OHTAKE Fumiaki The University of Tokyo, 分子細胞生物学研究所, 助教 (60447373)
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| Project Period (FY) |
2009 – 2010
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| Keywords | ユビキチン / 転写制御 / 環境 |
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| Research Abstract |
The data shows that ubiquitination and degradation of the dioxin receptor (AhR) are regulated by the histone acetyltransferase CBP.
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[Journal Article] PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B.2011
Author(s)
Baba A, Ohtake F, Okuno Y, Yokota K, Okada M, Imai Y, Ni M, Meyer CA, Igarashi K, Kanno J, Brown M, Kato S.
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Journal Title
Nat Cell Biol. (published on line)
Peer Reviewed
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[Journal Article] DNA demethylation in hormone-induced transcriptional derepression.2009
Author(s)
Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K, Shibuya H, Ohtake F, Kato S.
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Journal Title
Nature. 461(7266)
Pages: 1007-1012
Peer Reviewed
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[Journal Article] Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+mice with natural ligands.2009
Author(s)
Kawajiri K, Kobayashi Y, Ohtake F, Ikuta T, Matsushima Y, Mimura J, Pettersson S, Pollenz RS, Sakaki T, Hirokawa T, Akiyama T, Kurosumi M, Poellinger L, Kato S, Fujii-Kuriyama Y.
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Journal Title
Proc Natl Acad Sci U S A. 106(32)
Pages: 13481-13486
Peer Reviewed
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