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2010 Fiscal Year Final Research Report

Effect of hydration and cavity on protein dynamics studied by neutron scattering and simulation

Research Project

  • PDF
Project/Area Number 21770178
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biophysics
Research InstitutionJapan Atomic Energy Agency

Principal Investigator

NAKAGAWA Hiroshi  Japan Atomic Energy Agency, 量子ビーム応用研究部門, 研究員 (20379598)

Project Period (FY) 2009 – 2010
Keywordsタンパク質 / 中性子 / シミュレーション / ダイナミクス
Research Abstract

It was demonstrated that the protein internal dynamics is coupled with the dynamics of hydration water on protein surface and cavity in protein structure. This study will contribute not only bioscience but also food science because the decay of food is related with water and there is food processing by high pressure.

  • Research Products

    (12 results)

All 2011 2010 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (8 results) Book (2 results)

  • [Journal Article] Percolation of Hydration Water as a Control of Protein Dynamics2010

    • Author(s)
      H.Nakagawa, M.Kataoka
    • Journal Title

      Journal of Physical Society of Japan 79

      Pages: 083801

    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition2008

    • Author(s)
      H.Nakagawa, H.Kamikubo, M.Kataoka
    • Journal Title

      Biochimica et Biophysca Acta 1804

      Pages: 27-33

    • Peer Reviewed
  • [Presentation] Dynamics and hydration of intrinsically disordered protein studied by inelastic neutron scattering.2011

    • Author(s)
      中川洋
    • Organizer
      第1回ISIDP国際シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2011-01-27
  • [Presentation] Expectation to detect correlated dynamics in protein2011

    • Author(s)
      中川洋, 他
    • Organizer
      nDDB Discussion Meeting
    • Place of Presentation
      グルノーブル(フランス)
    • Year and Date
      2011-01-10
  • [Presentation] 中性子非弾性散乱によるタンパク質の揺らぎと水和水ダイナミクスの研究2010

    • Author(s)
      中川洋
    • Organizer
      日本中性子科学会第10回年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-12-09
  • [Presentation] 中性子非弾性散乱と分子動力学によるタンパク質の揺らぎと水和水ダイナミクスの研究2010

    • Author(s)
      中川洋, 他
    • Organizer
      日本物理学会2010年秋季大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
  • [Presentation] Dynamics of Biomolecules by Neutron Inelastic Scattering2010

    • Author(s)
      中川洋
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-20
  • [Presentation] 中性子非弾性散乱によるタンパク質の低エネルギーダイナミクスに対する水和効果2010

    • Author(s)
      中川洋, 他
    • Organizer
      日本物理学会第65回年次大会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-10
  • [Presentation] タンパク質ダイナミクスの調和運動と非調和運動に対する水和効果2009

    • Author(s)
      中川洋, 他
    • Organizer
      第9回日本中性子科学会年会
    • Place of Presentation
      東海
    • Year and Date
      2009-12-09
  • [Presentation] Hydration affects both harmonic and anharmonic nature of protein dynamics2009

    • Author(s)
      中川洋, 他
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Year and Date
      2009-10-30
  • [Book] Water, The Forgotten Biological Molecule2011

    • Author(s)
      Kataoka M., Nakagawa H.
    • Total Pages
      49-62
    • Publisher
      Pan Stanford Publishing
  • [Book] Neutrons in Soft Matter, John Wiley2011

    • Author(s)
      Kataoka M., Nakagawa H.
    • Total Pages
      517-538

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Published: 2012-02-13   Modified: 2016-04-21  

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