2010 Fiscal Year Final Research Report
Identification and characterization of novel proteins regulating epithelial barrier functions
| Project/Area Number |
21770210
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Cell biology
|
|---|
| Research Institution | Kobe University |
|---|
Principal Investigator |
IZUMI Yasushi Kobe University, 医学研究科, 助教 (10373268)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Keywords | 遺伝学 / 遺伝子 / 昆虫 / 細胞・組織 / 発生・分化 |
|---|
| Research Abstract |
Septate junctions (SJs) are specialized intercellular junctions, which restrict the free diffusion of solutes through the paracellular route in invertebrate epithelia. Here, we identified a novel cell adhesion protein Mesh and found that this protein is essential for the formation of endoderm-specific SJs, smooth SJs and the intestinal barrier function in Drosophila midgut.
|
Research Products
(4 results)
