2010 Fiscal Year Final Research Report
Molecular developmental study of the mammalian middle ear evolution
Project/Area Number |
21770259
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Evolutionary biology
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Research Institution | The Institute of Physical and Chemical Research |
Principal Investigator |
TAKECHI Masaki The Institute of Physical and Chemical Research, 形態進化研究グループ, 研究員 (10455355)
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Project Period (FY) |
2009 – 2010
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Keywords | 中耳 / 中耳腔 / 耳小骨 / 咽頭弓 / 顎骨弓 / 一次顎関節 / 形態進化 / Evo-Devo |
Research Abstract |
We reviewed previous comparative morphological and molecular developmental studies regarding the evolution of the mammalian middle ear and proposed that the most important issue in the evolution is "How did the tympanic membrane form in the lower jaw domain in the mammalian ancestor?" (Takechi and Kuratani, 2010). We next examined chicken and mouse embryos to identify mammal-specific developmental events which led the tympanic membrane in the lower jaw domain. Our data suggested that a dorsal shift of the primary jaw joint (articulation in the quadrate and articular) with respect to the first pharyngeal pouch in the mammalian ancestor led the tympanic membrane in the lower jaw domain.
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[Presentation] Molecular Developmental Study of the Mammalian Middle Ear Evolution.2011
Author(s)
Takechi, M., Hirai, T., Adachi,N., Hirasawa, T., Kuratani, S
Organizer
The 20th CDB meeting : Molecular Bases for Evolution of Complex Traits
Place of Presentation
Kobe, Japan.
Year and Date
2011-02-23
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