2010 Fiscal Year Final Research Report
Search for novel families of terpene cyclases from bacteria and analyses of physiological functions and bioactivities of C35 terpenes
| Project/Area Number |
21780109
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | Niigata University |
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Principal Investigator |
SATO Tsutomu Niigata University, 自然科学系, 准教授 (80334655)
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| Project Period (FY) |
2009 – 2010
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| Keywords | テルペン / テルペン環化酵素 / Mycobacterium / 枯草菌 |
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| Research Abstract |
A bifunctional Z-prenyltransferase that preferentially synthesize C_<35> or C_<50> products was found from the study on the mycobacterial C_<35> terpenes. The structure of two novel C_<35> terpenes suggested that a prenyl reductase reducing both E and Z prenyl residues was responsible for the biosynthesis of C_<35> terpenes. On the other hand, a novel family of terpene cyclases and tetraprenyl-β-curcumene cyclase from Bacillus subtilis could be identified by the in vitro enzymatic reaction.
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Research Products
(18 results)
