2010 Fiscal Year Final Research Report
Pathogen specific innate immune responses in fish
Project/Area Number |
21780194
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Fisheries chemistry
|
Research Institution | Tokyo University of Marine Science and Technology |
Principal Investigator |
KONDO Hidehiro Tokyo University of Marine Science and Technology, 海洋科学技術研究科, 准教授 (20314635)
|
Project Period (FY) |
2009 – 2010
|
Keywords | 魚類病原微生物 / 魚類免疫学 / 自然免疫応答 / 分子生物学 / マイクロアレイ |
Research Abstract |
Genes differently expressed in a pathogenic microorganisms specific manner were identified and the regulation mechanisms of their expression were evaluated in fish, especially for Japanese flounder. In response to bacteria, a number of immune-related genes were strongly induced by Gram-negative bacteria rather than by Gram-negative bacteria. In response to viruses, gene expression profiles were strongly influenced by rearing temperatures.
|