2010 Fiscal Year Final Research Report
Study on Novel Enantiotopic Group Selective Enyne Metathesis Reaction by Chiral Ruthenium Catalyst
| Project/Area Number |
21790002
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Chemical pharmacy
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
SAITO Nozomi Hokkaido University, 大学院・薬学研究院, 准教授 (80349258)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Keywords | 有機化学 |
|---|
| Research Abstract |
In order to create new class of chiral building blocks, enantiotopic groupselective intramolecular ene-yne metathesis reaction using ruthenium carbene complex bearing a chiral N-heterocyclic carbene ligand was investigated. As a result, a cyclic compound having a tetra-subustituted carbon atom was produced up to 34% ee.
|
