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2010 Fiscal Year Final Research Report

Studies on evaluating quality of highly-functional pharmaceuticals using dielectrophoresis

Research Project

  • PDF
Project/Area Number 21790046
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Physical pharmacy
Research InstitutionNational Institute of Health Sciences

Principal Investigator

SAKAI-KATO Kumiko  National Institute of Health Sciences, 薬品部, 室長 (10398901)

Project Period (FY) 2009 – 2010
KeywordsナノDDS製剤 / 誘電泳動 / モノリス型カラム / 分析化学
Research Abstract

It was found that the dielectrophoresis induced by alternating voltage could differentiate the accumulation rates of nano-meter sized drug carriers depending on the existence of the incorporated drugs. We also tried to analyze the nano-meter sized drug carriers using monolithic capillary column in order to apply the dielectrophoresis to chromatography.

  • Research Products

    (16 results)

All 2011 2010 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (9 results) Remarks (1 results)

  • [Journal Article] Controlled structure and properties of silicate nanoparticle networks for incorporation of biosystem components2011

    • Author(s)
      Sakai-Kato, K., Hasegawa, T., Takaoka, A., Kato, M., Toyo'oka, T., Utsunomiya-Tate, N., Kawanishi, T
    • Journal Title

      Nanotechnology 22

      Pages: 205702

    • Peer Reviewed
  • [Journal Article] ナノテクノロジーを応用した製剤に関する評価とその課題2011

    • Author(s)
      加藤くみ子
    • Journal Title

      薬剤学 71

      Pages: 114-117

  • [Journal Article] Analysis of intracellular doxorubicin and its metabolites by ultra-high-performance liquid chromatography2010

    • Author(s)
      Sakai-Kato, K., Saito, E., Ishikura, K., Kawanishi, T
    • Journal Title

      J.Chromatogr. B878

      Pages: 1466-1470

    • Peer Reviewed
  • [Journal Article] Development of high-performance analytical methods using biomolecules encapsulated in silicate nanomaterials.2010

    • Author(s)
      Sakai-Kato, K
    • Journal Title

      Chromatography 31

      Pages: 17-22

    • Peer Reviewed
  • [Journal Article] 高機能性DDS製剤の品質特性評価研究2009

    • Author(s)
      加藤くみ子
    • Journal Title

      PharmStage vol 9 No.9

      Pages: 1-2

  • [Journal Article] Integration of biomolecules into analytical systems by means of silica sol-gel technology.2009

    • Author(s)
      Sakai-Kato, K., Ishikura, K
    • Journal Title

      Analytical Sciences 25

      Pages: 969-984

    • Peer Reviewed
  • [Presentation] 製剤に用いられるシリカナノ粒子の物性評価に関する研究2011

    • Author(s)
      加藤くみ子, 水端美保,大島裕希, 川西徹
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-29
  • [Presentation] モノリス型キャピラリーカラムを用いたナノ粒子のサイズ分離手法の開発2010

    • Author(s)
      加藤くみ子, 齋藤栄子, 竹内豊英, 川西徹
    • Organizer
      第21回クロマトグラフィー科学会議
    • Place of Presentation
      西宮
    • Year and Date
      2010-10-23
  • [Presentation] Current initiatives in Japan for nanomedicines2010

    • Author(s)
      Sakai-Kato, K., Kawanishi, T
    • Organizer
      First international workshop on nanomedicines, European Medicines,招待講演
    • Place of Presentation
      Agency, London
    • Year and Date
      2010-09-03
  • [Presentation] ナノ粒子製剤のサイズ特性評価に関する検討2010

    • Author(s)
      加藤くみ子、齋藤栄子、石倉恵子、川西徹
    • Organizer
      第26回日本DDS学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-17
  • [Presentation] ナノ粒子DDS製剤の細胞内動態評価に関する基礎的研究2010

    • Author(s)
      加藤くみ子、石倉恵子、鈴木琢雄、多田稔、石井明子、山口照英、川西徹
    • Organizer
      日本薬剤学会第25回年会
    • Place of Presentation
      徳島
    • Year and Date
      2010-05-14
  • [Presentation] 超高速LCを用いたドキソルビシン内包DDS製剤の体内動態評価に向けた研究2010

    • Author(s)
      加藤くみ子、齋藤栄子、石倉恵子、川西徹
    • Organizer
      第130回日本薬学会年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
  • [Presentation] 生体物質の機能解析と高性能分離分析法への応用2009

    • Author(s)
      加藤くみ子
    • Organizer
      第20回クロマトグラフィー科学会議,招待講演
    • Place of Presentation
      東京
    • Year and Date
      2009-11-12
  • [Presentation] ナノ粒子DDS製剤の細胞内動態可視化に関する基礎的研究2009

    • Author(s)
      加藤くみ子、石倉恵子、鈴木琢雄、石井明子、山口照英、川西徹
    • Organizer
      第18回日本バイオイメージング学会学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2009-09-03
  • [Presentation] 高機能性製剤の品質評価法の開発2009

    • Author(s)
      加藤くみ子
    • Organizer
      第22回バイオメディカル分析科学シンポジウム,招待講演
    • Place of Presentation
      岐阜
    • Year and Date
      2009-07-16
  • [Remarks] ホームページ等

    • URL

      http://www.nihs.go.jp/drug/DrugDiv-J.html

URL: 

Published: 2012-02-13   Modified: 2016-04-21  

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