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2011 Fiscal Year Final Research Report

Three-dimensional analyses of embryonic development in humans using episcopic fluorescence image capture(EFIC)

Research Project

  • PDF
Project/Area Number 21790180
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General anatomy (including Histology/Embryology)
Research InstitutionKyoto University

Principal Investigator

YAMADA Shigehito  京都大学, 医学研究科, 准教授 (80432384)

Project Period (FY) 2009 – 2011
Keywords先天異常学 / 奇形学 / 発生学
Research Abstract

Rapid advances in medical imaging are facilitating the clinical assessment of first trimester human embryos at increasingly earlier stages. To obtain data on early human development, we used episcopic fluorescence capture(EFIC) to acquire digital images of human embryos spanning the time of dynamic tissue remodeling and organogenesis(Carnegie stages 13 to 23). Using these imaging datasets, 3D reconstructions were generated for visualizing different anatomical structures and further morphometrical analyses.

  • Research Products

    (9 results)

All 2012 2011 2010 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (3 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Digitization of clinical and epidemiological data from the Kyoto Collection of Human Embryos2012

    • Author(s)
      Kameda T, Yamada S, Uwabe C, Suganuma N
    • Journal Title

      Congenital Anomlaies

      Volume: 52(1) Pages: 48-54

    • DOI

      DOI:10.1111/j.1741-4520.2011.00349.x.

    • Peer Reviewed
  • [Journal Article] Developmental atlas of the early first trimester human embryo2010

    • Author(s)
      Yamada S, Lee ES, Samtani RR, Lockett E, Uwabe C, Shiota K, Anderson SA, Lo CW
    • Journal Title

      Dev Dyn

      Volume: 239(6) Pages: 1585-95

    • Peer Reviewed
  • [Journal Article] MR顕微鏡とepiscopic fluorescence image capture(EFIC)法を用いたヒト胚子のイメージング-中枢神経系を中心に-2010

    • Author(s)
      塩田浩平、山田重人、土屋真衣子、巨瀬勝美
    • Journal Title

      小児の脳神経

      Volume: 35(1) Pages: 7-10

    • Peer Reviewed
  • [Presentation] 「妊婦の疫学データベースを用いた胚子奇形発生に関する要因の検討.先天異常データベースの網羅的解析2011

    • Author(s)
      亀田知美、白川康一、土屋真衣子、山崎茉莉、上部千賀子、塩田浩平、山田重人
    • Organizer
      第51回日本先天異常学会
    • Place of Presentation
      東京
    • Year and Date
      20110722-24
  • [Presentation] Construction and Application of Human Embryo Database2011

    • Author(s)
      Yamada S, Kameda T, Takahashi M, Funatomi T, Mizuta S, Matsuda Y, Haishi T, Kose K, Matsuda T, Minoh M, Uwabe C, Shiota K
    • Organizer
      Teratology Society 51^<st> Annual Meeting
    • Place of Presentation
      San Diego, California, USA
    • Year and Date
      20110625-0629
  • [Presentation] Embryo imaging : Episcopic fluorescence image capture(EFIC) for experimental animals2010

    • Author(s)
      Yamada S, Tsuchiya M, Kameda T, Komada M, Shiota K.
    • Organizer
      Teratology Society 50^<th> Annual Meeting
    • Place of Presentation
      Louisville, Kentucky, USA
    • Year and Date
      20100626-30
  • [Book] The Human Embryo2012

    • Author(s)
      Edited by Yamada S, Takakuwa T
    • Total Pages
      180
    • Publisher
      InTech
  • [Book] Fine Biomedical Imaging Using X-Ray Phase-Sensitive Technique In : Advanced Biomedical Engineering/Book 2(Edited by : Gaetano D. Gargiulo, Co-editor : Alistair McEwan)2011

    • Author(s)
      Yoneyama A, Yamada S, Takeda T
    • Total Pages
      280
    • Publisher
      InTech
  • [Remarks] ホームページ等データベースの一部が公開されている。

    • URL

      http://bird.cac.med.kyoto-u.ac.jp

URL: 

Published: 2013-07-31  

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