2010 Fiscal Year Final Research Report
Study on the molecular mechanism of hormone secretion
| Project/Area Number |
21790197
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General physiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TSUBOI Takashi The University of Tokyo, 大学院・総合文化研究科, 准教授 (80415231)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 開口放出 / ミオシン2 / マイクロRNA / ホルモン / 神経内分泌細胞 / バイオイメージング / 細胞骨格 / 分泌顆粒 |
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| Research Abstract |
To adapt environmental changes, endocrine tissues in our body are secreted variety of hormones to maintain body homeostasis. Failure of this mechanism is directly linked to various disease such as diabetes and allergies. In the present study, we identified an myosin 2 as a regulator for hormone secretion by using biochemical, physiological, and bioimaging analyses.
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Research Products
(32 results)
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[Journal Article] Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells.2011
Author(s)
Ohata S, Aoki R, Kinoshita S, Yamaguchi M, Tsuruoka-Kinoshita S, Tanaka H, Wada H, Watabe S, Tsuboi T, Masai I, Okamoto H.
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Journal Title
Peer Reviewed
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