2010 Fiscal Year Final Research Report
An examination of entrainment mechanisms of the peripheral clock
| Project/Area Number |
21790230
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Kinki University |
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Principal Investigator |
SUJINO Mitsugu Kinki University, 医学部, 助教 (30460843)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 生物時計 |
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| Research Abstract |
To elucidate the entrainment mechanisms of the peripheral clock, we carried out a series of experiments using the glucocorticoid injection and restricted feeding with a relationship of a reverse phase mutually. The results indicated the differences of the dominant timing factor among kinds of organs. The peripheral clock of the kidney and lung entrained to the time of corticosterone administration. In contrast, the liver clock was synchronized to the time of feeding.
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