2010 Fiscal Year Final Research Report
Modulation of insulin sensitivities by the PIP3 phosphatase, SKIP
| Project/Area Number |
21790276
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | Kobe University |
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Principal Investigator |
IJUIN Takeshi 神戸大学, 大学院・医学研究科, 助教 (00361626)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 基礎医学 |
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| Research Abstract |
Insulin stimulates glucose uptake into skeletal muscle cells. Decreased insulin sensitivity caused hyperglycemia, which increases the risk for Type II diabetes and atherosclerosis. In this study, I have shown that the PIP3 phosphatase, SKIP, modulated insulin sensitivities in the skeletal muscle.
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