2010 Fiscal Year Final Research Report
The Identification of Genes Associated with Radiation-related Thyroid Cancer by Genome Wide Association Analysis
| Project/Area Number |
21790337
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human genetics
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| Research Institution | Kyoto University |
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Principal Investigator |
TAKAHASHI Meiko Kyoto University, 医学研究科, 助教 (20372592)
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| Project Period (FY) |
2009 – 2010
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| Keywords | ゲノム医科学 |
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| Research Abstract |
The main aim of this research is to identify the SNPs associated with the risk of radiation-related thyroid cancer. We have started genome wide association analyses of thyroid cancer patients who were aged 0-18 years and resided in the radio-contaminated regions of Belarus at the time of the Chernobyl accident, and matched Belarusian control subjects.
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[Journal Article] The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.2010
Author(s)
Meiko Takahashi, Vladimir Saenko, Tatiana Rogounovitch, Takahisa Kawaguchi, Valentina Drozd, Hisako Takigawa-Imamura,Natallia Akulevich, Chanavee Ratanajaraya, Norisato Mitsutake, Noboru Takamura, Larisa Danilova, Maxim Lushchik, Yuri Demidchik, Simon Heath, Ryo Yamada, Mark Lathrop, Fumihiko Matsuda, Shunichi Yamashita.
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Journal Title
Human Molecular Genetics Vol.19
Pages: 2516-2523
Peer Reviewed
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