2010 Fiscal Year Final Research Report
Pathologic analyses of developmental mechanisms and biological characteristics of breast neuroendocrine tumors (B-NET)
| Project/Area Number |
21790347
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | University of Yamanashi |
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Principal Investigator |
KAWASAKI Tomonori University of Yamanashi, 大学院・医学工学総合研究部, 助教 (90456484)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 泌尿生殖器 / 内分泌 |
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| Research Abstract |
We have described breast neuroendocrine ductal carcinoma in situ (NE-DCIS) as having characteristic clinicopathological features, such as bloody nipple discharge, low frequency of preoperative diagnosis and low-grade pathological parameters, allowing differentiation from non-NE-DCIS and, consequently, delineating this carcinoma as a distinctive variant of DCIS (Histopathology, 2008. Cytopathology, 2011. Pathol Int, 2011. J Clin Pathol, 2011. USCAP, 2010 & 2011). NE-DCIS is a tumor entity which is important for understanding the histogenesis and natural history of breast neuroendocrine tumors (B-NET), because NE-DCIS can be regarded as a preinvasive counterpart of B-NET.
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