Definition of human cardiomyogenic differentiation factor

2012 Fiscal Year Final Research Report

• Project/Area Number: 21790373
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Human pathology
• Research Institution: Kyoto Prefectural University of Medicine (2011-2012); Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology (2010); Yokohama National University (2009)
• Principal Investigator: KAMI Daisuke 京都府立医科大学, 医学研究科, 助教 (80415588)
• Project Period (FY): 2009 – 2012
• Keywords: 分化誘導 / 心筋細胞 / 液性因子 / 遺伝子導入 / 心筋分化 / 間葉系幹細胞

Research Abstract

Differentiation into cardiomyocytes is depended to cell differentiated state, expression genes, and extracellular environment. This idea could play important role in next step for cardiomyogenic differentiation.

Research Products

• [Journal Article] Impaired CXCL4 expression in tumor-associated macrophages (TAMs) of ovarian cancers arising in endometriosis (2012)
  • Author(s): Furuya M, Tanaka R, Miyagi E, Kami D, Nagahama K, Miyagi Y, Nagashima Y, Hirahara F, Inayama Y, Aoki I.
  • Journal Title: Cancer Biol Ther Volume: 13(8) Pages: 671-680
  • Peer Reviewed
• [Journal Article] Expression of angiotensin II receptor-like 1 in the placentas of pregnancy-induced hypertension (2012)
  • Author(s): Furuya M, Okuda M, Usui H, Takenouchi T, Kami D, Nozawa A, Shozu M, Umezawa A, Takahashi T, Aoki I
  • Journal Title: Int J Gynecol Pathol Volume: 31(3) Pages: 227-235
  • Peer Reviewed
• [Journal Article] Placenta to Cartilage: Direct conversion of human placenta to chondrocytes with transformation by defined factors (2012)
  • Author(s): Kami D, Ishii R, Toyoda M, Makino H, Gojo S, Ishii T, Umezawa A
  • Journal Title: Mol Biol Cell. Volume: 23(18) Pages: 3511-21
  • DOI: doi:10.1091/mbc.E11-10-0869.Epub2012Jul25
  • Peer Reviewed
• [Journal Article] Amniotic membrane-derived mesenchymal stromal cell transplantation (2012)
  • Author(s): Kimura M, Toyoda M, Gojo S Itakura Y, Kami D, Miyoshi S, Kyo S, Ono M, Umezawa A
  • Journal Title: J Stemcells & Regenerative Med Volume: Vol8 No.3 Pages: 171-180
  • Peer Reviewed
• [Presentation] Efficient Transfection method using the Magnetic nanoparticles and Episomal vector (2012)
  • Author(s): Daisuke Kami, Masashi Toyoda, Atsushi Kishida, Osam Mazda, Akihiro Umezawa, Masatoshi Watanabe, Hiroaki Matsubara, Satoshi Gojo
  • Organizer: 9th International Conference on the Scientific and Clinical Use of Magnetic Carriers
  • Place of Presentation: University of Minnesota
  • Year and Date: 20120000
• [Presentation] ヒト右心耳由来心筋幹細胞の遺伝子導入による心筋分化誘導 (2012)
  • Author(s): 上大介, 豊田雅士, 板倉陽子, 松原弘明, 梅澤明弘, 五條理志
  • Organizer: 第11回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 20120000
• [Presentation] iPS 細胞の早期・効率的取得を目指したキャピラリー等電点電気泳動法の開発 (2012)
  • Author(s): 上大介、高橋慎、豊田雅士、松原弘明、関澤隆一、渡邉昌俊、梅澤明弘、五條理志
  • Organizer: 第11回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 20120000
• [Presentation] CONSTRUCTION OF LARGE AMOUNTS CULTURE SYSTEM BY AN AUTOMATED CELL PROCESSING MACHINE FOR THE CELL TRANSPLANTATION (2012)
  • Author(s): Daisuke Kami, Masashi Toyoda, Mayu Yamazaki-Inoue, Naofumi Takehara, Takehiro Ogata, Hiroaki Matsubara, Akihiro Umezawa, Satoshi Gojo
  • Organizer: International Society for Stem Cell Research 10th Annual Meeting
  • Place of Presentation: Yokohama
  • Year and Date: 20120000
• [Presentation] BASIC RESEARCH OF THE IMMUNO ASSAY BY THE CAPILLARY ISOELECTRIC FOCUSING FOR EFFICIENT ACQUISITION OF THE IPS CELL (2012)
  • Author(s): Daisuke Kami, Makoto Takahashi, Masashi Toyoda, Ryuichi Sekizawa, Hiroaki Matsubara, Akihiro Umezawa, Satoshi Gojo
  • Organizer: International Society for Stem Cell Research 10th Annual Meeting
  • Place of Presentation: Yokohama
  • Year and Date: 20120000
• [Presentation] DEVELOPMENT OF HIGH EFFICIENT GENE DELIVERY SYSTEM USING EPISOMAL VECTOR AND MAGNETIC NANOPARTICLES FOR PRODUCTION OF IPSCS (2012)
  • Author(s): Daisuke Kami, Masashi Toyoda, Atsushi Kishida, Osam Mazda, Hiroaki Matsubara,Akihiro Umezawa, Satoshi Gojo
  • Organizer: International Society for Stem Cell Research 10th Annual Meeting
  • Place of Presentation: Yokohama
  • Year and Date: 20120000
• [Presentation] PLACENTA TO CARTILAGE: DIRECT CONVERSION OF HUMAN PLACENTA TO CHONDROCYTES WITH TRANSFORMATION BY DEFINED FACTORS (2012)
  • Author(s): Daisuke Kami, Ryuga Ishii, Masashi Toyoda, Hatsune Makino, Satoshi Gojo,Akihiro Umezawa
  • Organizer: ISSCR-Roddenberry International Symposium on Cellular Reprogramming
  • Place of Presentation: GLADSTONE INSTITUTES, San Francisco
  • Year and Date: 20120000