2010 Fiscal Year Final Research Report
Generation and maintenance of memory CD8+Tcells against malaria infection
| Project/Area Number |
21790409
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Nagasaki University |
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Principal Investigator |
MIYAKODA Mana Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (30398151)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 原虫 |
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| Research Abstract |
We tried to examine why generation of immunological memory was suppressed against malaria infection. The experiments resulted in that memory CD8+T cells could be generated after malaria infection. However, during re-infection with malaria parasite, both trafficking and expansion of memory cells were suppressed, suggesting that those are one of the mechanisms that generation of immunological memory is suppressed against malaria infection
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