2010 Fiscal Year Final Research Report

Research to clarify the factor which effect to the value of prostate specific antigen among men undergoing health checkup.

Research Project

Project/Area Number	21790566
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Hygiene
Research Institution	National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Principal Investigator	SAWADA Norie 独立行政法人国立がん研究センター, がん予防・検診研究センター, 研究員 (00446551)
Project Period (FY)	2009 – 2010
Keywords	癌 / 前立腺特異高原
Research Abstract	Previous studies have shown relationships between lifestyle and prostate-specific antigen (PSA), a commonly used serum marker for the detection and diagnosis of prostate cancer. To examine the association between anthropometry and intake of soy food and PSA in Japanese men, we analyzed 4722 apparently healthy Japanese men who visited our screening for cancer from February 2004 to January 2009. There was significantly inverse correlation between height, weight, BMI and PSA levels. Intake of soy food, genistein and daidzein at baseline was significantly inversely correlated with PSA among men with over 30 or more BMI.