2010 Fiscal Year Final Research Report
Elusidation of a regulatory mechanism by Peroxiredoxin 6 (Prx-6) in inflammatory bowel desease(IBD
Project/Area Number |
21790680
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Gastroenterology
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Research Institution | Kyoto Prefectural University of Medicine |
Principal Investigator |
OKADA Hitomi Kyoto Prefectural University of Medicine, 医学研究科, 助教(寄附講座) (60533023)
|
Project Period (FY) |
2009 – 2010
|
Keywords | 腸管炎症性疾患 / 酸化ストレス |
Research Abstract |
It is suggested that Peroxiredoxin 6 (Prx-6) may provide cytoprotection and wound healing in YAMC cells. Ulcerative colitis (UC) patients were treated using granulocytapheresis (GCAP). After the treatment, Prx6 in the patients, which observed the therapeutic effect, increased. These results show that Prx-6 may be involved in mechanisms of inflammatory bowel disease (IBD) and be used as a marker of examination the therapeutic effect of IBD.
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Research Products
(2 results)