2010 Fiscal Year Final Research Report
Protective role of PEDF in transgenic diabetic nephropathy mouse.
| Project/Area Number |
21790824
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Kidney internal medicine
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| Research Institution | Kurume University |
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Principal Investigator |
MATSUI Takanori Kurume University, 医学部, 助教 (10425233)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 糖尿病 / シグナル伝達 |
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| Research Abstract |
Pigment epithelium derived factor (PEDF) is expected to lead to improved therapies for the treatment of diabetic nephropathy. To clarify whether PEDF improves early-stage diabetic nephropathy by antioxidative stress activities, production of transgenic mouse which express of PEDF is induced by tetracycline was attempted.
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