2010 Fiscal Year Final Research Report
The role of fatty acid elongation enzyme Elovl6 through cannabinoid receptor in a hippocampus
| Project/Area Number |
21790860
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Metabolomics
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| Research Institution | University of Tsukuba |
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Principal Investigator |
ISHII Kiyoaki University of Tsukuba, 大学院・人間総合科学研究科, 助教 (80419150)
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| Project Period (FY) |
2009 – 2010
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| Keywords | カンナビノイド / エネルギー代謝 |
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| Research Abstract |
Influence to proliferation and differentiation was observed by a glia cell and a nerve cell of Elovl6 KO mouse hippocampus. Because 2-AG amount of the endogenous cannabinoid receptor agonist decreases by a hippocampus of KO mouse, a possibility that cannabinoid cascade through 2-AG can consider.
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Research Products
(4 results)
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[Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.2010
Author(s)
Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H.
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Journal Title
Biochemical and biophysical research communications 391(2)
Pages: 1222-1227
Peer Reviewed
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[Journal Article] The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice.2009
Author(s)
Nakanishi N, Nakagawa Y, Tokushige N, Aoki N, Matsuzaka T, Ishii K, Yahagi N, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Urayama O, Yamada N, Shimano H.
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Journal Title
Biochemical and biophysical research communications 385(4)
Pages: 492-496
Peer Reviewed
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