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2011 Fiscal Year Final Research Report

the hepatic immune therapy for metabolic disease

Research Project

  • PDF
Project/Area Number 21790882
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Metabolomics
Research InstitutionKeio University

Principal Investigator

IRIE Junichiro  慶應義塾大学, 医学部, 助教 (70306687)

Project Period (FY) 2009 – 2011
Keywords糖尿病 / 脂肪肝
Research Abstract

NAFLD(nonalcoholic fatty liver disease) is recently recognized as not only the consequence but also the cause of metabolic disorders, but the precise mechanisms of NAFLD remain unclear. Here we have shown that the immune systems are essential for the development of NAFLD and the cytokines could be the therapeutic targets of NAFLD leading to the improvement of metabolic syndromes.

  • Research Products

    (5 results)

All 2011 2010 2009

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results)

  • [Journal Article] The Role of Hepatic T Lymphocytes in the Induction of Fatty Liver and Diabetes2011

    • Author(s)
      Hirotsune Tagawa, Junichiro Irie, Arata Itoh, Yukie Soeda, Satoru Yamada, Hiroshi Itoh
    • Journal Title

      Clinical and Experimental Hypertension

      Volume: 33(1) Pages: 15

    • Peer Reviewed
  • [Presentation] 肝脂肪蓄積・糖脂質代謝異常を引き起こす肝内Tリンパ球の検討2011

    • Author(s)
      伊藤新, 入江潤一郎, 田川裕恒, 加藤麻里, 添田幸恵, 山田悟, 伊藤裕
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
  • [Presentation] 肝内免疫担当細胞の制御による肝脂肪化と糖脂質代謝の調節2010

    • Author(s)
      伊藤新, 入江潤一郎, 田川裕恒, 添田幸恵, 伊藤裕
    • Organizer
      第53回日本糖尿病学会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-29
  • [Presentation] Tリンパ球の糖脂質代謝・肝脂肪蓄積への影響の検討2009

    • Author(s)
      田川裕恒、入江潤一郎、伊藤新、添田幸恵、山田悟、伊藤裕
    • Organizer
      第45回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-05
  • [Presentation] Tリンパ球の糖脂質代謝への影響の検討2009

    • Author(s)
      田川裕恒、入江潤一郎、伊藤新、添田幸恵、山田悟、伊藤裕
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23

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Published: 2013-07-31  

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