2010 Fiscal Year Final Research Report
Searching for the subcutaneous adipose tissue-derived factor that improves insulin resistance.
Project/Area Number |
21790900
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Endocrinology
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Research Institution | National Cardiovascular Center Research Institute |
Principal Investigator |
MIYAZAWA Takashi 独立行政法人国立循環器病研究センター, 生化学部, 客員研究員 (30443500)
|
Project Period (FY) |
2009 – 2010
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Keywords | 内分泌 / インスリン抵抗性 / 生理活性ペプチド / 脂肪組織 |
Research Abstract |
The metabolic syndrome, which is a recognized risk factor for cardiovascular diseases, is associated with visceral fat accumulation and insulin resistance. In this study, to identify newly endogenous factors that improve insulin resistance in liver, we developed the new assay systems and identified the insulin-like growth factor II (IGF-2) from the adipose tissues.
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