2010 Fiscal Year Final Research Report
Association between innate immunity and pathophysiology of Kawasaki disease
| Project/Area Number |
21790993
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Kyushu University |
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Principal Investigator |
池田 和幸 Kyushu University, 医学研究院・成長発達医学分野, 九州大学病院小児科講師 (30507786)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 川崎病 / 自然免疫 |
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| Research Abstract |
Both microarray and quantitative RT-PCR analyses have shown that the innate immune system might be involved in the pathogenesis and pathophysiology of Kawasaki disease. NOD Ligands enhance ICAM-1 expression and cytokine production by human coronary artery endothelial cells in vitro.
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[Journal Article] A novel SCN5A mutation associated with the linker between III and IV domains of Na(v)1.5 in a neonate with fatal long QT syndrome.2010
Author(s)
Yamamura K, Muneuchi J, Uike K, Ikeda K, Inoue H, Takahata Y, Shiokawa Y, Yoshikane Y, Makiyama T, Horie M, Hara T
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Journal Title
Int J Cardiol 145
Pages: 61-64
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