2010 Fiscal Year Final Research Report
Determination of the cause of Long QT Syndrome in children
| Project/Area Number |
21791031
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Embryonic/Neonatal medicine
|
|---|
| Research Institution | Yamagata University |
|---|
Principal Investigator |
OTAGIRI Tesshu Yamagata University, 医学部, 助教 (30400550)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Keywords | QT延長症候群 / 遺伝性不整脈 / イオンチャネル / ブルガダ症候群 |
|---|
| Research Abstract |
We carried out genetic analysis of Long-QT Syndrome(LQT), an inherited cardiac arrhythmia, in five unrelated LQT families. DNA sequence analyses revealed KCNQ1 mutations(LQT1) in three families and KCNH2 mutations(LQT2) in two families. Genetic analysis may provide a useful tool for diagnosis and management of LQT.
|
