A study regarding gene expressions of Retrotransposon-like 1 in human placentas of intrauterine growth restriction

2010 Fiscal Year Final Research Report

• Project/Area Number: 21791034
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Embryonic/Neonatal medicine
• Research Institution: Kobe University
• Principal Investigator: MORIOKA Ichiro Kobe University, 医学部附属病院, 助教 (80437467)
• Research Collaborator: FUJIOKA Kazumichi 神戸大学, 医学部附属病院, 臨床研究員 (20568810)
• Project Period (FY): 2009 – 2010
• Keywords: 子宮内胎児発育遅延 / 胎盤 / レトロトランスポゾン由来遺伝子(Retrotransposon-like 1 : Rtl1)

Research Abstract

A purpose of this study was to find abnormal expressions of Retrotransposon-like 1 gene (Rtl1) in human placentas of intrauterine growth restriction (IUGR). We found for the first time that different expressions of Rtl1 were observed in human placentas of IUGR and healthy newborns.

Research Products

• [Journal Article] Does thrombocytopenia contribute to patent ductus arteriosus? (2011)
  • Author(s): Fujioka K, Morioka I, Miwa A, Morikawa S, Shibata A, Yokoyama N, Matsuo M.
  • Journal Title: Nat Med. 17 Pages: 29-30
  • Peer Reviewed
• [Journal Article] VEGF 936C>T is Predictive of Threshold Retinopathy of Prematurity in Japanese Infants with Gestational Age of 30 weeks or less. (2011)
  • Author(s): Yagi M, Yamamori M, Morioka I, Yokoyama N, Honda S, Nakamura T, Okamura N, Okumura K, Negi A, Sakaeda T, Matsuo M.
  • Journal Title: Research and Reports in Neonatology. 1 Pages: 5-11
  • Peer Reviewed
• [Journal Article] Genetic disorders associated with neonatal jaundice. (2010)
  • Author(s): Morioka I, Morikawa S, Yusoff S, Harahap IS, Nishimura N, Yokoyama N, Matsuo M, Van Rostenberghe H, Nishio H.
  • Journal Title: Eastern Journal of Medicine. 15 Pages: 155-162
• [Journal Article] The lowest surviving birth weight infant from a systemic lupus erythematosus mother with antiphospholipid syndrome. (2010)
  • Author(s): Fujioka K, Morioka I, Urade T, Suzuki K, Morizane M, Yokoyama N, Matsuo M.
  • Journal Title: J Matern Fetal Neonatal Med. 23 Pages: 1050-1052
  • Peer Reviewed
• [Presentation] Does Thrombocytopenia Increase the Risk for Patent Ductus Arteriosus in Japanese Premature Newborns? (2011)
  • Author(s): Fujioka K, Morioka I, Matsuo K, Yokota T, Hashimoto F, Morikawa S, Miwa A, Shibata A, Yokoyama N, Matsuo M.
  • Organizer: The Society for Pediatric Research Conference
  • Place of Presentation: Denver USA
  • Year and Date: 20110430-20110503
• [Presentation] 極低出生体重児の精神運動発達の特徴～子宮内胎児発育の程度と発達的な偏り～ (2010)
  • Author(s): 万代ツルエ、森岡一朗、三輪明弘、北山真次、横山直樹、松尾雅文
  • Organizer: 第104回日本小児精神神経学会
  • Place of Presentation: 徳島
  • Year and Date: 20101113-20101114
• [Presentation] 重症子宮内胎児発育不全児における尿道下裂合併症例とその出生時臨床像の検討 (2010)
  • Author(s): 藤岡一路、森岡一朗、松尾希世美、横田知之、森川悟、三輪明弘、柴田暁男、横山直樹、松尾雅文
  • Organizer: 第55回日本未熟児新生児学会
  • Place of Presentation: 神戸
  • Year and Date: 20101105-20101107
• [Presentation] 子宮内胎児発育遅延の病態解明に向けて～-2SD未満のSGA児の周産期背景についての検討～ (2009)
  • Author(s): 藤岡一路、森岡一朗、橋本総子、齋藤敦郎、森川悟、三輪明弘、柴田暁男、横山直樹、松尾雅文
  • Organizer: 第54回日本未熟児新生児学会
  • Place of Presentation: 横浜
  • Year and Date: 20091129-20091201
• [Presentation] 極低出生体重児として出生した重症子宮内胎児発育不全児の3歳時の身体発育と精神運動発達の検討 (2009)
  • Author(s): 森岡一朗、橋本総子、斎藤敦郎、藤岡一路、森川悟、三輪明弘、柴田暁男、横山直樹、松尾雅文
  • Organizer: 第54回日本未熟児新生児学会
  • Place of Presentation: 横浜
  • Year and Date: 20091129-20091201
• [Presentation] 極低出生体重児として出生した重症子宮内胎児発育不全児の3歳時の頭囲と精神運動発達の検討 (2009)
  • Author(s): 万代ツルエ、森岡一朗、北山真次、横山直樹、松尾雅文
  • Organizer: 第102回日本小児精神神経学会
  • Place of Presentation: 名古屋
  • Year and Date: 20091116-20091117
• [Presentation] 重症子宮内胎児発育遅延児の発達 (2009)
  • Author(s): 森岡一朗
  • Organizer: 第29回乳幼児の発達を考える会
  • Place of Presentation: 神戸
  • Year and Date: 2009-11-25