2010 Fiscal Year Final Research Report
Pathological analysis of Bronchopulmonary Dysplasia using Exhaled Breath Condensates
| Project/Area Number |
21791038
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Kyushu University |
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Principal Investigator |
GOTO Takako Kyushu University, 大学病院, その他(医員) (20467947)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 未熟児医学 |
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| Research Abstract |
We obtained exhaled breath condensates (EBCs) from extremely low birth weight infants whose birth weights were less than 1000g. And we examined associations EBCs with clinical symptoms of bronchopulmonary dysplasia, which is one of the respiratory complications with those infants. There was not any correlation pH in EBCs to the symptoms, including severity (p=0.77), steroid hormone administration (p=0.36), oxygenation therapy period (r=-0.277, p=0.89), mechanical ventilation period (r=0.21, p=0.29), and CT score (r=0.03, p=0.88). Most of the cytokines and chemokines in EBCs were not detected in the cytometric beads array. There was limitation of methods of measurement due to little amount of EBCs.
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