2010 Fiscal Year Final Research Report
Development of a novel therapy targeting new intracellular receptors for the treatment of malignant melanoma
| Project/Area Number |
21791057
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | Hirosaki University |
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Principal Investigator |
MATSUZAKI Yasushi Hirosaki University, 医学部附属病院, 講師 (50322946)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 皮膚腫瘍学 |
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| Research Abstract |
I confirmed that cultured melanoma cells expressed RIG-I protein by IFN-βstimulation. Moreover, the levels of the IFN-β-induced RIG-I expression was dependent on the types of melanoma cell lines. It is necessary to identify intracellular signals via RIG-I in various melanoma cells.
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Research Products
(10 results)
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[Journal Article] Raf kinase inhibitor protein expression correlates with differentiation but not with ERK phosphorylation in cutaneous squamous cell carcinoma.2010
Author(s)
Rokunohe D, Nakano H, Akasaka E, Kimura K, Takiyoshi N, Nakajima K, Aizu T, Kaneko T, Matsuzaki Y, Tsuchida S, Sawamura D.
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Journal Title
J Dermatol Sci. 60(3)
Pages: 199-201
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