2011 Fiscal Year Final Research Report
Development of next-generation system for aiding design of repeated radiotherapy
| Project/Area Number |
21791224
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Kagawa University (2010-2011)
Kawasaki University of Medical Welfare (2009) |
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Principal Investigator |
UEMURA Koji 香川大学, 医学部附属病院, 准教授 (00308199)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 非線形位置合わせ / 放射線治療 / がん / 局所再発 / 線量分布 / DICOM-RT |
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| Research Abstract |
In this study, we developed a method for obtaining the reliable mutual relationship of location among the dose distribution of a few times irradiation with some intervals using the 3-dimensional nonlinear registration. In the patients who received several times radiotherapy, the earlier CT image was realigned to the later CT image by the nonlinear registration, and the transformational parameters were obtained. Next, dose-distribution image of each irradiation was generated from the DICOM-RT Plan, Structure Set, Dose, Image information, and the dose-distribution image of the earlier radiotherapy was realigned to that of the later radiotherapy by the transformational parameters obtained from the registration of CT images. This transformed image of the previous irradiation was converted to the DICOM-RT format, and displayed on the CT image acquired for a new radiotherapy. As a result, the error of registration was smaller than 3mm by an expert' s visual inspection. The proposed system would be valuable for designing a new radiotherapy by referring to a dose distribution of previous irradiations.
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