2011 Fiscal Year Final Research Report
Fundamental experiments for a quantitative myocardial blood flow measurement in 3D-PET
| Project/Area Number |
21791237
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | National Institute of Radiological Sciences (2011)
National Cardiovascular Center Research Institute (2009-2010) |
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Principal Investigator |
HIRANO Yoshiyuki 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 博士研究員 (00423129)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 3D-PET / 散乱線補正 / 心筋血流 / モンテカルロシミュレーション |
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| Research Abstract |
Accuracy of quantitative myocardial blood flow(MBF) measurements using 3D-PET depends on activity distribution, especially outside filed-of-view(FOV) distribution. We investigated the influence on quantification of MBF by fundamental phantom experiments and a sophisticated Monte Carlo simulation. The effects of outside FOV activity were not critical for quantification of MBF. Especially, a MBF measurement by O-15 water was less insensitive to scatter originated from outside FOV activity.
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