2010 Fiscal Year Final Research Report
Multifaceted study of gastrointestinal functions after pancreaticoduodenectomy.
| Project/Area Number |
21791302
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Digestive surgery
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
AKIZUKI Emi Sapporo Medical University, 医学部, 研究員 (20404626)
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| Research Collaborator |
HIRATA Koichi 札幌医科大学, 医学部, 教授 (50136959)
YASUTOSHI Kimura 札幌医科大学, 医学部, 講師 (80311893)
TAKAYUKI Nobuoka 札幌医科大学, 医学部, 助教 (50404603)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 膵臓外科学 / 膵頭十二指腸切除術 / 胃内容排出遅延 / 消化管機能 |
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| Research Abstract |
This study was planned to evaluate the post-pancreaticoduodenectomy (PD) oral intake tolerance. Perioperative data were prospectively collected in all patients, and the patient's postoperative dietary intake was recorded for all meals until discharge. The occurrence of delayed gastric emptying (DGE) and the amount of dietary intake were analyzed. The risk factors for low oral intake tolerance were additionally determined. As a result, gender (women), BMI (>25kg/m^2), postoperative intraabdominal infection, and DGE were significantly associated with low oral intake tolerance. Additionally, upper gastrointestinal contrast examination, and blood stream analysis by a CT Perfusion method were performed to study postoperative gastrointestinal functions. These results had possibilities to investigate the cause of postoperative low oral intake tolerance.
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