2010 Fiscal Year Final Research Report
Temsirolimus, mTOR Inhibitor, Inhibits Progression of Malignant Pleural Mesothelioma in Vitro.
| Project/Area Number |
21791316
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Kanazawa University |
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Principal Investigator |
TAMURA Masaya Kanazawa University, 附属病院, 助教 (10397185)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 悪性胸膜中皮腫 / 分子標的治療 / PI3K-AKT-mTOR経路 |
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| Research Abstract |
The results suggest the therapeutic efficacy of temsirolimus against MPM in vitro. And it is expected that temsirolimus inhibits MPM growth not only by anticancer effect but by antangiogenic effect in vivo.
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