2010 Fiscal Year Final Research Report
Brain neural circuit remodeling in the Olfactory system
| Project/Area Number |
21791353
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Shinshu University |
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Principal Investigator |
KAWAGISHI Kyutaro Shinshu University, 医学部, 助教 (40313845)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 神経再生 / 神経機能再生 / 嗅覚 |
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| Research Abstract |
Recovery of olfaction following the lateral olfactory tract (LOT) transection was examined in developing and adult animals. After complete LOT transection was made in P2 neonatal rats and 12w adult rats, olfactory discriminative ability was tested. Olfaction was well preserved in the P2 rat group, but not in the 12w adult rat group. These data indicate that neonatal rat brain has neural plasticity after brain injury resulting in re-establishment of olfactory neural circuit and preservation of olfactory function.
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