2012 Fiscal Year Final Research Report
Pathophysiology of steroid-induced osteonecorsis
| Project/Area Number |
21791402
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2012
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| Keywords | 骨壊死 |
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| Research Abstract |
We assessed which part of the femoral head was the key point of a collapse, and also examined whether a collapsed region was associated with the size of necrotic lesion. Then, the results suggested that a collapse may begin at the lateral boundary of the necrotic lesion, and the size of the necrotic lesion seemed to contribute to the distribution of a collapse. We also examined the reparative process of osteonecrosis using SPECT/CT with 99mTc methylene diphosphonate. Then, during the time before collapse, there was a gradual increase in the tracer uptake around the necrotic lesion, shifting the main region from anteriorly to laterally.
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