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2011 Fiscal Year Final Research Report

Satisfactory emergence from general anesthesia and its mechanisms

Research Project

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Project/Area Number 21791429
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Anesthesiology/Resuscitation studies
Research InstitutionTohoku University

Principal Investigator

OHTANI Norimasa  東北大学, 大学院・歯学研究科, 大学院非常勤講師 (60338879)

Project Period (FY) 2009 – 2011
Keywords麻酔薬 / 覚醒状態 / デクスメデトミジン / 術後痛 / エスモロール
Research Abstract

When co-administered with sevoflurane and propofol, the increasing doses of dexmedetomidine did not prolong emergence time from general anesthesia. IT administration of esmolol produced antinociceptive effects of short duration in a postoperative pain rat model.

  • Research Products

    (4 results)

All 2011 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] Perioperative infusion of dexmedetomidine at a high dose reduces postoperative analgesic requirements : A randomized control trial2011

    • Author(s)
      Ohtani N, Yasui Y, Watanabe D, Kitamura M, Shoji S, Masaki E
    • Journal Title

      J Anesth

      Volume: 25 Pages: 872-878

    • Peer Reviewed
  • [Journal Article] Postoperative pain status after intraoperative administration of dexmedetomidine as a general anesthetic adjuvant2009

    • Author(s)
      Yasuda M, Tachibana Y, Aoi A, Kurihara J, Ohtani N, Masaki E
    • Journal Title

      Tohoku Univ Dent J

      Volume: 28 Pages: 43-48

    • Peer Reviewed
  • [Presentation] Efficacy of intrathecal esmolol on heat-evoked responses in postoperative pain model2010

    • Author(s)
      Ohtani N, Tachibana Y, Aoi A, Yasui Y, Masaki E
    • Organizer
      The 2010 annual meeting of American society of Anesthesiologist
    • Place of Presentation
      San Diego, California
    • Year and Date
      2010-10-15
  • [Presentation] The lateralized pain processing in the central amygdale of the rat model of neuropathic pain2010

    • Author(s)
      Yasui Y, Ikeda, Takahashi Y, Masaki E, Shoji K, Ohtani N, Kitamura S, Kato F
    • Organizer
      3rd International Congress on Neuropathic Pain
    • Place of Presentation
      Greece, Athens
    • Year and Date
      2010-05-28

URL: 

Published: 2013-07-31  

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