2010 Fiscal Year Final Research Report
SNP analysis of SCF-Kit gene in patients with or without OAB
| Project/Area Number |
21791516
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Nagoya City University |
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Principal Investigator |
KUBOTA Yasue Nagoya City University, 大学院・医学研究科, 講師 (00381830)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 過活動膀胱 / Kit / 間質細胞 |
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| Research Abstract |
KIT is not only a detection marker of these cells, but also may play a crucial role in the control of bladder function. Research into the effect of c-kit receptor inhibitor, imatinib mesylate, on bladder function implies that KIT-positive ICCs may be therapeutic target cells to reduce bladder overactivity and that the blockage of c-kit receptor may offer a new therapeutic strategy for OAB treatment.
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